"As a starting point in this 2010 article, Comparing the microbiota of the cystic fibrosis lung and human gut which states 'the typically mutually beneficial relationships usually found in the GI tract from the injurious relationships in the CF [Cystic Fibrosis] lung.' This is a familiar situation of the disease altering the microbiotia, with the microbiotia then supporting the disease. This was illustrated in the diagram below.
For CF, this is reported in this 2004 article, Intestinal inflammation is a frequent feature of cystic fibrosis and is reduced by probiotic administration."
Cystic Fibrosis and Microflora / Gut Bacteria / Microbiota | Chronic Fatigue Syndrome: